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Patients receiving placebo were six times more likely to discontinue treatment because of lack of treatment effect than patients receiving cyclophosphamide.

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Pulmonary toxicity occurred in two patients (11%) with one death (6%) because of IP.

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Patients had "chemosensitive or stable disease after salvage treatment.

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It includes two drugs: doxorubicin (Adriamycin), and cyclophosphamide (Cytoxan).


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Almost all medications are safe to take with Cyclophosphamide.

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Astragalus may increase the potency of antiviral medications such as acyclovir or interferon, thereby worsening the potential side effects of these drugs (such as possible kidney failure and other side effects).

Also, because so many small beamlets are being used, the dose of radiation going to the tumor may not be as even as is usually seen with 3D conformal therapy.

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