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It helps. I get a really distinct nausea in the night, maybe once a month. I know it when I wake up feeling sick and then my whole body starts to heat up. I take Zofran right away. I still have episodes of almost vomiting, dry heaves I guess, but it keeps it down. Takes a few hours for the symptoms to subside-usually means I'm up half the night, but I'm terrified of throwing up so this is one of the best prevention medicines. This and ginger tea are my go-to remedies. That said, if I don't fully sleep it off I end up with a hangover in the morning.
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A generic drug simply means that the drug is not made by the original manufacturer, the chemical is exactly the same. To make sure our entire product list is in stock, the orders are sent out directly by our manufacturer. All medications are obtained from legitimate pharmaceutical wholesalers, so you can rest assured you are receiving the same medication as you would at your neighborhood pharmacy. Generic drugs manufacturers do not need to spend huge amounts on scientific research and development, on extensive clinical trials and marketing campaigns. To put it differently generics have identical active ingredients and their pharmacological effects are the same, as those of their brand-name equivalents. If you know what product you need just use the search engine at the main page or see full products list, you may find needed product at the left side of the main page at the corresponding section as well. When the product is found just add it to the cart and follow further instructions.


I have been suffering from Meniere's disease (it is an inner ear disorder causing severe vertigo and nausea) for more than 5 years. it is when you turn into a shaky vomiting wreck, as if all your life is a non-stop seasickness. At first it was sheer hell for me as I couldn't go anywhere, couldn't spend time with my friends and so on, but then my doc put me on Zofran and things got back to normal. God bless the men and women who created this drug. It truly works miracles for people like me.

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There have been reports of liver failure and death in patients with cancer receiving concurrent medications including potentially hepatotoxic cytotoxic chemotherapy and antibiotics.

It should also be noted that when nitrous oxide is used, the fresh gas flow should be increased during emergence to enhance the washout of nitrous oxide.

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These costs of some of the antiemetics have decreased dramatically during recent years as generic versions have become available and also vary to a large extent from country to country and among different institutions.

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Ondansetron (Zofran) and the second-generation antihistamines cetirizine (Zyrtec) and fexofenadine (Allegra) do not reduce symptoms of motion sickness and should not be used.

Moses LE, Shapiro D, Littenberg B: Combining independent studies of a diagnostic test into a summary ROC curve: data-analytic approaches and some additional considerations.

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We found that the inhibition of 5-HT synthesis by PCPA significantly increased glucose uptake into BAT ().

Orally Disintegrating Tablets is ondansetron base, the racemic form of ondansetron, and a selective blocking agent of the serotonin 5-HT 3 receptor type.

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The effects of prophylactic ephedrine, ondansetron and placebo were compared.

Drugs and Foods to Avoid Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Due to lack of specific evidence of cause of diarrhea, organism(s), dosage, and product availability, a specific recommendation for the use of probiotics in prevention of AGE is unable to be made (Sazawal et al.

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Combinations involving metoclopramide are not found to reduce PONV to a greater extent than monotherapy.

Cases of transient blindness, predominantly during intravenous administration, have been reported.

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Inform patients that Ondansetron may cause hypersensitivity reactions, some as severe as anaphylaxis and bronchospasm.

Talk to your doctor or pharmacist if you have any questions.

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If the risk of PONV is very high, 20% of patients receiving an optimal prophylactic dose of ondansetron (8 mg given intravenously or 16 mg given orally) will not vomit who would have vomited had they received placebo.

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In vitro metabolism studies have shown that ondansetron is a substrate for multiple human hepatic cytochrome P-450 enzymes, including CYP1A2, CYP2D6, and CYP3A4.

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Any patient requiring admission was considered a treatment failure, and no further doses were given.

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Patients were excluded for clinically significant cardiac, hepatic, or renal disease.

Ondansetron may increase the risk of developing prolongation of the QT interval of the electrocardiogram.

Yonemura M, Katsumata N, Hashimoto H, Randomized controlled study comparing two doses of intravenous granisetron (1 and 3 mg) for acute chemotherapy-induced nausea and vomiting in cancer patients: A non-inferiority trial.

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Articles reporting the results of a variety of clinical trials, review articles, and reports of case studies were reviewed and scored.

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Ondansetron is a prescription medication used to prevent nausea and vomiting caused by chemotherapy or surgery.

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Aprepitant was significantly more effective than ondansetron for preventing vomiting at 24 and 48 h after surgery, and in reducing nausea severity in the first 48 h after surgery.

Deb, I'd recommend seeing a neurologist, ideally one that specializes in pain management.

The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongation.

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MK-0869) to a 5-HT 3 receptor antagonist plus dexamethasone before cisplatin chemotherapy improved the control of acute emesis, compared with a 5-HT 3 receptor antagonist plus dexamethasone; this regimen also improved the control of delayed emesis, compared with placebo.

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Oral Solution is ondansetron hydrochloride (HCl) as the dihydrate, the racemic form of ondansetron and a selective blocking agent of the serotonin 5-HT 3 receptor type.

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Cyclic vomiting syndrome was first described in the medical literature in 1806 in French, and 1882 in English.

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This may partly explain why 4 mg is widely believed to be the most effective intravenous ondansetron dose to prevent PONV.

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Ondansetron is a highly potent antiemetic drug that is effective in preventing chemotherapy-and radiation-induced nausea and vomiting with a very low risk of adverse effects.

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Outcomes Associated with 5-HT3-RA Therapy Selection in Patients with Chemotherapy-Induced Nausea and Vomiting: A Retrospective Claims Analysis.

Tolerance to this opioid-induced nausea and vomiting usually occurs within days to weeks.

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