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This study found that, compared with once-daily losartan 50 mg, once-daily telmisartan 80 mg reduced 24-hour mean blood pressure and blood pressure variability, and improved glucose tolerance and insulin sensitivity.

Patients with NSTE-ACS and a recent history of cocaine or methamphetamine use should be treated in the same manner as patients without cocaine- or methamphetamine-related NSTE-ACS.

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SPCs also resulted in significantly more patients reaching BP goal compared with A5.

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When these guidelines are used as the basis for regulatory or payer decisions, the goal should be improvement in quality of care.

Bedtime ingestion of hypertension medications reduces the risk of new-onset type 2 diabetes: a randomised controlled trial.

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High risk for CV events can be evidenced by a history of coronary artery disease, peripheral arterial disease, stroke, transient ischemic attack, or high-risk diabetes (insulin dependent or non-insulin dependent) with evidence of end-organ damage.

The name of this family of peptides is currently an unsettled issue.

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Participation in an intensive therapy program requires a motivated patient, but it can dramatically reduce eye, nerve, and renal complications compared to conventional therapy.

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Shaefer reports personal fees from Sanofi, Eli Lilly, AstraZeneca, Boehringer Ingelheim, Janssen, Forest Pharmaceuticals, and Vivus; and nonfinancial support from Sanofi outside the submitted work.

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The average daily doses were 17 mg of enalapril, 19 mg of lisinopril, 80 mg of captopril, 6 mg of ramipril, and 23 mg of quinapril.

Therefore, to provide clinically relevant information, trials evaluating ARBs in these patients must include proven doses of an ACE inhibitor, either as background therapy or as a comparator.

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Continued surveillance can assess both response to therapy and progression of disease.

In the placebo-controlled factorial design study, the population treated with a Telmisartan and Amlodipine combination had a mean age of 53 years and included approximately 50% males, 79% were Caucasian, 17% Blacks, and 4% Asians.

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